2025 5th GC Conference Institute of Cancer Research London, UK

2025
5th GC Conference
Institute of Cancer Research London, UK

The 5th GC Conference, hosted by the Institute of Cancer Research (ICR), continues this powerful legacy – uniting families, scientists, and foundations to accelerate discovery, share breakthroughs, and honor the children whose courage drives every step forward. This year, three competitive research grants – $100,000 each – were awarded to advance innovative studies on Gliomatosis Cerebri, marking one of the conference’s most significant investments in scientific progress to date.

RESEARCH GRANT WINNERS

Systemic and Intratumoral Immune Profiling

Maria Vinci, PHD | Ospedale Pediatrico Bambino Gesù | Rome, Italy

The study aims to generate a comprehensive resource of the GC patients’ immune system, analysing peripheral blood and matched tumour samples. This approach will reveal how the disease affects systemic immunity and how immune-tumour cell interactions shape the tumour microenvironment.

Towards a Multimodal Atlas of Glioma Diffuseness

Jeffrey P. Greenfield, MD, PhD | Weill Cornell Medicine | New York, USA

This groundbreaking project seeks to establish the first-ever standardized scoring system for tumor diffusiveness, a vital tool that will unlock critical insights into cancer biology. This tool will help answer key questions: Was GC a truly distinct disease, or one extreme of a broader spectrum? What biological programs drive tumors to spread? Most importantly, how can this knowledge inform treatment and improve patient outcomes?

Identifying and Targeting a Dominant Myeloid—Tumor Axis in Pediatric Gliomatosis Cerebri

Dannis van Vuorden, MD, PhD | Marietta E.G. Kranendonk, MD, PhD Princess Máxima Center for Pediatric Oncology | Netherlands

The overall aim of the research is to identify the dominant myeloid—tumor signaling pathway driving the diffuse infiltrative pattern of gliomatosis cerebri (GC) and to validate its therapeutic blockade, with brain delivery achieved through focused ultrasound-mediated blood—brain barrier opening (FUS-BBBO).

To know more about the GC Conferences please contact us or visit us at the GC Global Community Facebook Page or email as us at gliomatosiscerebri@gmail.com

DYNAMIC FOOTER WILL BE HERE