{"id":375,"date":"2026-10-21T19:36:33","date_gmt":"2026-10-21T19:36:33","guid":{"rendered":"https:\/\/rightstopbd.com\/gliomatosiscerebri\/?page_id=375"},"modified":"2026-10-31T18:20:00","modified_gmt":"2026-10-31T18:20:00","slug":"2017-2nd-gc-conference-national-institutes-of-health-maryland-usa","status":"publish","type":"page","link":"https:\/\/rightstopbd.com\/gliomatosiscerebri\/2017-2nd-gc-conference-national-institutes-of-health-maryland-usa\/","title":{"rendered":"2017 2nd GC Conference National Institutes of Health | Maryland, USA"},"content":{"rendered":"[vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_color=”#595959″ scene_position=”center” top_padding=”2%” constrain_group_1=”yes” bottom_padding=”2%” text_color=”light” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” row_position_desktop=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text css=”” text_direction=”default”]\n

2017
\n2nd GC Conference
\nNational Institutes of Health | Maryland, USA<\/h2>\n[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” top_padding=”2%” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” row_position_desktop=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_gallery css=”” type=”flickity_style” images=”448,449,450″ flickity_spacing=”default” flickity_controls=”pagination” flickity_overflow=”hidden” flickity_wrap_around=”wrap” flickity_desktop_columns=”1″ flickity_small_desktop_columns=”1″ flickity_tablet_columns=”1″ flickity_phone_columns=”1″ flickity_free_scroll=”true” flickity_autoplay=”true” flickity_autorotate_type=”ticker” flickity_ticker_speed=”medium” flickity_box_shadow=”none” image_loading=”default” onclick=”link_no” nectar_slider_autorotate_dur=”5000″][\/vc_column][\/vc_row][vc_row type=”in_container” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” scene_position=”center” bottom_padding=”2%” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” row_position_desktop=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text css=”” text_direction=”default”]The Second International Gliomatosis Cerebri (GC) Conference convened at the National Institutes of Health (NIH) on June 22-23, 2017, bringing together a multidisciplinary community of family advocates, clinicians, researchers, and scientific experts committed to advancing the understanding of this devastating disease.<\/p>\n

Building on the momentum from the First International Gliomatosis Cerebri Conference, participants from the United States and the United Kingdom gathered to assess scientific progress, strengthen international collaboration, and define strategic priorities for future research.<\/p>\n

The conference focused on accelerating efforts to better understand GC biology while developing impactful collaborative initiatives to drive meaningful advances over the next two years.<\/p>\n

Through extensive discussions and scientific exchange, attendees identified three high-priority areas for collaborative investigation:[\/vc_column_text][divider line_type=”No Line” custom_height=”20″][vc_column_text css=”” text_direction=”default”]\n

The Second Gliomatosis Cerebri Conference Provocative Projects<\/strong><\/h2>\n

 <\/p>\n

Project 1: Sequencing and target identification<\/h3>\n

This project focuses on GC tissue sequencing and target identification. The plan is creating an international GC registry for a comprehensive study on GC biology. According to their report, \u201cGC is heterogeneous, often with a solid and an infiltrative portion, experts recommended that tumor tissue should be sampled from more than one site, with emphasis on tissue samples from any solid tumor component or central tumor as well as infiltrative part.\u201d<\/p>\n

Project 2: Evaluating the potential of immunotherapy<\/h3>\n

Focused on the evaluation of the potential of immunotherapeutic for patients with GC, particularly given the exceptional response of a patient with GC on a Phase 1 study of radiation therapy administered with the immunomodulatory agent, lenalidomide [18]. There are multiple unknowns in this patient population including baseline immune function, immunosuppressive mechanisms in the tumor microenvironment and if this differs from those with other malignant glioma phenotypes, and presence or absence of tumor-specific antigens. To identify target antigens, tumor samples need to be studied genetically with single-cell RNA sequencing and the exploration of tumors microenvironment. Several studies have described a synergistic effect of radiation therapy with immunotherapy and this opportunity should be explored in GC [19, 20].<\/p>\n

It was further planned that projects on immunotherapy should be linked to the GC registry (Project 1) so that tumor tissue and response to immunotherapy can be systematically studied.<\/p>\n

Project 3: Clinical Translation<\/h3>\n

This third project is to for GC-specific pre-clinical and patient-related research. However, the lack of understanding of the biology of GC made the group agree instead to initially focus first on preclinical studies on GC invasiveness. These clinical studies will then be subsequently projected to be built upon this work.<\/p>\n

A 2-year timeline was also targeted for each of these provocative projects.[\/vc_column_text][\/vc_column][\/vc_row][vc_row type=”full_width_background” full_screen_row_position=”middle” column_margin=”default” column_direction=”default” column_direction_tablet=”default” column_direction_phone=”default” bg_color=”#6E6E6E” scene_position=”center” top_padding=”4%” constrain_group_1=”yes” bottom_padding=”4%” text_color=”dark” text_align=”left” row_border_radius=”none” row_border_radius_applies=”bg” row_position_desktop=”default” row_position_tablet=”inherit” row_position_phone=”inherit” overflow=”visible” overlay_strength=”0.3″ gradient_direction=”left_to_right” shape_divider_position=”bottom” bg_image_animation=”none” gradient_type=”default” shape_type=””][vc_column column_padding=”no-extra-padding” column_padding_tablet=”inherit” column_padding_phone=”inherit” column_padding_position=”all” flex_gap_desktop=”10px” column_element_direction_desktop=”default” column_element_spacing=”default” desktop_text_alignment=”default” tablet_text_alignment=”default” phone_text_alignment=”default” background_color_opacity=”1″ background_hover_color_opacity=”1″ column_backdrop_filter=”none” column_shadow=”none” column_border_radius=”none” column_link_target=”_self” column_position=”default” gradient_direction=”left_to_right” overlay_strength=”0.3″ width=”1\/1″ tablet_width_inherit=”default” animation_type=”default” bg_image_animation=”none” border_type=”simple” column_border_width=”none” column_border_style=”solid”][vc_column_text css=”” text_direction=”default”]\n

DYNAMIC FOOTER WILL BE HERE<\/span><\/p>\n[\/vc_column_text][\/vc_column][\/vc_row]\n","protected":false},"excerpt":{"rendered":"

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